Dr.Lijuan Yuan
Professor
Biomedical Science
Orcid identifier0000-0003-0709-5228
- ProfessorBiomedical Science
- Virginia Polytechnic Institute and State University, Department of Biomedical Sciences and Pathobiology, 1981 Kraft Drive, Room 2034, Blacksburg, VA, 24061-0913, United States
BIO
Dr. Lijuan Yuan is a full Professor of Virology and Immunology at the Department of Biomedical Sciences and Pathobiology at Virginia Polytechnic Institute and State University, Blacksburg, Virginia. She received a master’s degree in virology and immunology at the Laboratory of Biochemistry and Immunology, the Capital Institute of Pediatrics, Beijing, China; a Ph.D. degree in virology and immunology at the Food Animal Health Research Program, Department of Veterinary Preventive Medicine, The Ohio State University, Ohio, USA in 2000; and completed her post-doctoral training at the Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health (NIH), Bethesda, Maryland, USA in 2002.
Dr. Yuan's research interest focuses on host-pathogen interactions in enteric viruses including infectivity, pathogenesis and immunity, and on intervention strategies to reduce viral diarrhea including prophylactics, therapeutics, vaccines and influences of probiotics/prebiotics and gut microbiota. Her lab has studied the pathogenesis of human rotavirus and norovirus, the immunogenicity and protective efficacy of various rotavirus and norovirus vaccines, adjuvants and immunization routes using gnotobiotic (Gn) pigs as a model. The findings from Gn pigs are highly translatable to humans because pigs are genetically and immunologically similar to humans. The research activities in Yuan laboratory are supported by grants from NIH, Bill and Melinda Gates Foundation, PATH, and various international vaccine companies. She has published 120 scientific publications, including a monograph titled "Vaccine Efficacy Evaluation: The Gnotobiotic Pig Model". She has mentored 8 Ph.D. students as a major advisor (https://academictree.org/microbiology/tree.php?pid=275786) and an additional 18 Ph.D. students as a faculty advisory committee member. She teaches Molecular Virology lectures to graduate students and Emerging Infectious Diseases lectures to DVM students. She received Pfizer Award for Research Excellence in 2011, the Outstanding Graduate Mentor Award from Graduate School, Virginia Polytechnic Institute and State University in 2017, and Grant Turnwald Innovation Award from Virginia-Maryland College of Veterinary Medicine, 2020-2021.
Dr. Yuan's research interest focuses on host-pathogen interactions in enteric viruses including infectivity, pathogenesis and immunity, and on intervention strategies to reduce viral diarrhea including prophylactics, therapeutics, vaccines and influences of probiotics/prebiotics and gut microbiota. Her lab has studied the pathogenesis of human rotavirus and norovirus, the immunogenicity and protective efficacy of various rotavirus and norovirus vaccines, adjuvants and immunization routes using gnotobiotic (Gn) pigs as a model. The findings from Gn pigs are highly translatable to humans because pigs are genetically and immunologically similar to humans. The research activities in Yuan laboratory are supported by grants from NIH, Bill and Melinda Gates Foundation, PATH, and various international vaccine companies. She has published 120 scientific publications, including a monograph titled "Vaccine Efficacy Evaluation: The Gnotobiotic Pig Model". She has mentored 8 Ph.D. students as a major advisor (https://academictree.org/microbiology/tree.php?pid=275786) and an additional 18 Ph.D. students as a faculty advisory committee member. She teaches Molecular Virology lectures to graduate students and Emerging Infectious Diseases lectures to DVM students. She received Pfizer Award for Research Excellence in 2011, the Outstanding Graduate Mentor Award from Graduate School, Virginia Polytechnic Institute and State University in 2017, and Grant Turnwald Innovation Award from Virginia-Maryland College of Veterinary Medicine, 2020-2021.
ACADEMIC POSITIONS
- Full Professor of Virology (tenured)Virginia Polytechnic Institute and State University, Department of Biomedical Sciences and Pathobiology, Blacksburg, USAJun 2019
- Full Professor of VirologyVirginia Polytechnic Institute and State University, Faculty of Health Sciences for Translational Biology, Medicine, and Health Program, Blacksburg, United States10 Jun 2019
- Associate Professor of Virology (tenured)Virginia Polytechnic Institute and State University, Department of Biomedical Sciences and Pathobiology, Blacksburg, United States1 Jun 2013 - 30 Jun 2019
- Associate Professor of VirologyFaculty of Health Sciences for Translational Biology, Medicine, and Health Program, Virginia Polytechnic Institute and State University, United States2 Jun 2014 - 7 Jun 2019
- Academic VisitorUniversity of Melbourne, Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, Victoria, AustraliaOct 2015 - Apr 2016
- Assistant Professor of VirologyVirginia Polytechnic Institute and State University, Department of Biomedical Sciences and Pathobiology, Blacksburg, United States1 Jul 2007 - 1 Jun 2013
- Adjunct Assistant Professor and Research ScientistThe Ohio State University, FAHRP, Department of Veterinary Preventive Medicine, OARDC, Wooster, United States1 Jul 2002 - 30 Jun 2007
- Postdoctoral FellowNational Institutes of Health, National Institute of Allergy and Infectious Diseases, Bethesda, United States1 Sep 2000 - 1 Jun 2002
- Invited ConsultantVirology Institute, CICV, INTA, Castelar, Buenos Aires, Argentina15 Aug 2000 - 16 Sep 2000
- Graduate Research AssociateOhio State University, Food Animal Health Research Program, Department of Veterinary Preventative Medicine, OARDC, Wooster, United States1996 - 2000
- Visiting ScientistOhio State University, Food Animal Health Research Program, Department of Veterinary Preventative Medicine, OARDC, Wooster, United States1993 - 1996
- Assistant Research FellowCapital Institute of Pediatrics, Beijing Municipal Laboratory of Infection and Immunity, Beijing, China1991 - 1993
- Graduate Research AssociateCapital Institute of Pediatrics, Laboratory of Biochemistry and Immunology, Beijing, China1988 - 1991
- Research AssistantCapital Institute of Pediatrics, Laboratory of Biochemistry and Immunology, Beijing, China1986 - 1988
- Research AssistantCapital Institute of Pediatrics, Research and Development Center for Infants and Children's Food and Nutrition, Beijing, China1985 - 1986
NON-ACADEMIC POSITIONS
- Assistant PharmacistBeijing Thoracic Hospital, Beijing, China1981 - 1983
DEGREES
- Ph.D.Ohio State University, Columbus, United States1 Sep 1996 - 6 Jun 2000
- M.S.Capital Institute of Pediatrics, Beijing, China1 Aug 1988 - 1 Jul 1991
- Diploma, BiochemistryBeijing University, China1983 - 1985
- Diploma, PharmaceuticsBeijing Health School, China1978 - 1981
POSTGRADUATE TRAINING
- Section of Epidemiology, Laboratory of Infectious DiseasesNational Institutes of Health, National Institute of Allergy and Infectious Diseases, United StatesSep 2000 - Jul 2002
LANGUAGES
- EnglishCan read, write, speak, understand and peer review
- Chinese (Mandarin)Can read, write, speak, understand and peer review